19 Top VC Firms in San Francisco

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This article spotlights 19 of the top venture capital firms in San Francisco, the heart of tech innovation. These aren’t just any investors; they’re the movers and shakers who can turn your startup dreams into Silicon Valley success stories.

We’ll guide you through what sets each firm apart and whether they’re the right fit for your startup. Let’s dive in and connect you with the funding powerhouses of the Bay Area.

  1. 11.2 Capital

11.2 Capital was founded in 2013. The firm, based in California, focuses and invests in companies solving problems using emerging technologies. The firm brings a combination of technical background, operational experience, and a strong network of advisors and partners to support entrepreneurs. Areas where they provide support include technical recruiting, partnerships, customer introductions, and follow-on financings.

Headquarters: USA

Investment Geography: USA, UK, Canada, Germany

Operating since: 2013

Investment Focus: Enterprise Software (Cybersecurity, Analytics, Big Data, AI, ML), Smart Hardware (AR, VR, Robotics, Space,3D Printing, Automotive), Data-Driven Health Care (Biotechnology, Therapeutics, Diagnostics, Tools, Digital Health, Computational Health, Synthetic Biology)

Stages: Seed, Series A, Series B. 

Number of investments: 53 

Number of exits: 8

Check size: $500k – $5m

Notable investments: Cruise Automation, Hinge Health

Founders/Key People: Shelley Zhuang

Website: https://www.112capital.com 

  1. 1984 Ventures

1984 Ventures specializes in seed-stage investments, particularly focusing on founders with a strong engineering culture who are addressing real-world problems across various industries. 

They lean towards companies operating in diverse areas such as e-commerce, supply chain management, proptech, and healthcare. The VC firm supports founders with recruiting, fundraising, and founder therapy. 

Headquarters: USA

Investment Geography: USA, Mexico, Canada, Chile, Egypt, Netherlands, Colombia, Australia

Operating since: 2017

Investment Focus: Software (E-commerce, Supply Chain, PropTech, FinTech, HealthCare, SaaS, Consumer, Marketplaces, Staffing)

Stages: Seed

Number of investments: 104

Number of exits: 3

Check size: $500k – $1million

Notable investments: Postscript, Kyte, FairMarkIT

Founders/Key People: Ramy Adeeb, Aaron Michel

Website: https://1984.vc/

  1. Amity Ventures

Amity Ventures, founded in 2017 and based in San Francisco, is a venture capital firm known for supporting founders building category-defining businesses. They focus on a select few companies, offering more than just capital and emphasizing a hands-on partnership approach. The fund typically participates in investment rounds with 4-5 participants and is involved in 2-6 deals per year. The average startup value when Amity Ventures invests is between $500 million and $1 billion, and their typical deals range from $10 million to $50 million.

Headquarters: United States

Investment Geography: USA 

Operating since: 2017

Stages: Seed, Series A, Series B

Investment Focus: B2B SaaS, Enterprise Software, Cloud, AI, ML, Data Analytics, CyberSecurity, Mobile, Gaming, Consumer Internet, Semiconductors 

Number of investments: 54

Number of exits: 3

Check size: $10m- $50m

Notable investments: Snyl, CaptivateIQ

Founders/Key People: CJ Reim, Marcelino Pantoja

Website: https://www.amity.vc 

  1. Array Ventures

Array Ventures, a venture capital firm based in San Francisco, California, focuses on empowering early-stage startups through strategic guidance, equity-based investments, and a comprehensive ecosystem of services. Established in 2015, they specialize in investing in startups that use revolutionary technologies like artificial intelligence, machine learning, big data, and enterprise solutions to solve impactful problems and reshape industries. The firm primarily invests in the United States, particularly in companies that are about 2-3 years old and are in sectors like SaaS and machine learning​​​​​​​​​​​​.

Headquarters: USA

Investment Geography: USA, India, Netherlands, Sweden 

Operating since: 2015

Stages: Pre-Seed, Seed

Investment Focus: Enterprise DeepTech, Big Data, Artificial Intelligence, AI/ML, Workflow Automation, B2B (HealthTech, RetailTech, EdTech, CyberSecurity, SaaS, Communication) 

Number of investments: 79

Number of exits: 18

Check size: $1m – 3m

Notable investments: Oro Labs, XWING

Founders/Key People: Shruti Gandhi

Website: https://www.array.vc 

  1. ARTIS Ventures

ARTIS Ventures, founded in 2001 and based in San Francisco, California, specializes in pioneering investments at the intersection of life sciences and computer sciences, a niche known as TechBio. They have a track record of over a decade in supporting market-defining companies to reshape and reinvent industries. The firm is known for investing in early-stage and late-stage companies. ARTIS Ventures primarily invests in companies based in the United States. 

Headquarters: USA

Investment Geography: USA, UK, Germany

Operating since: 2001

Stages: Seed, Series A, Series B 

Investment Focus: TechBio (BioTech, Diagnostics, AI, MedTech, Data Analytics, Advanced Materials, FoodTech, Enterprise Software, HealthTech, Digital Health), Tech (Digital Media, Cloud Computing, ML, CyberSecurity, Data Storage, Semiconductors, FinTech, MR, SpaceTech, Marketplaces, Business Intelligence, FoodTech)

Number of investments: 128

Number of exits: 38

Check size: $500k – $10m

Notable investments: Palantir Technologies, YouTube

Founders/Key People: Stuart Peterson, Vasudev Bailey

Website: https://www.av.co 

  1. August Capital

August Capital is a VC firm established in 1995, based in Menlo Park, California, with a focus on the IT sector. The firm co-founded by David Marquardt and John Johnston, specializes in early-stage, later-stage, and startup investments. They like to invest in infrastructure, data center technologies, systems management, security, storage, and cloud computing systems. The firm manages about $2 billion in aggregate capital commitments.

Headquarters: USA

Investment Geography: USA, UK, Canada, Singapore, Japan, Poland, Ireland

Operating since: 1995

Stages: Seed, Series A, Series B

Investment Focus: AdTech, Aerial Imaging, Big Data and Machine Learning, Blockchain, Branding and Consumer Products, CDN, E-commerce, Enterprise Logistics, Financial Services, IoT, Marketplace Platform, Media and Content, Network Hardware, Networking and Cloud, SAAS, Security, Semiconductors, Social, Software and Systems, Storage Systems, Wireless Communications 

Number of investments: 392

Number of exits: 185

Check size: $400k – 2m

Notable investments: Avant, Inrix

Founders/Key People: Buddy Arnheim, Eric Carlborg

Website: https://www.augustcap.com

  1. AXA Venture Partners

AXA Venture Partners, established in 2015 and headquartered in Paris, France, is a prominent venture capital firm. It focuses on investing in high-growth, technology-enabled companies. The firm operates globally, with over $1.5 billion in assets under management. AVP invests across various stages, including seed-stage, early-stage, later-stage, and growth-stage companies. Its investment portfolio covers enterprise software, fintech/insurtech, consumer technologies, and digital health. Notably, AXA Venture Partners was formerly known as AXA Strategic Ventures.

Headquarters: France

Investment Geography: USA, UK, Canada, France, Israel, Switzerland, Netherlands, Germany, Spain, Italy

Operating since: 2015

Stages: Seed, Series A, Series B, Series C

Investment Focus: Enterprise Software, FinTech, Insurtech, Consumer Tech, Digital Health

Number of investments: 121

Number of exits: 29

Check size: $300k – $20m

Notable investments: Deskbird, Zinc

Founders/Key People: Manish Agarwal, François Robinet

Website: https://www.axavp.com 

  1. Azure Capital Partners

Azure Capital Partners is a popular early-stage VC firm in San Francisco. They specialize in identifying and investing in late-stage information technology companies. The firm is well-regarded for its industry thought leadership and uses a data-guided approach to strategic decision-making. Azure Capital Partners is generally involved in deals ranging from $10 million to $50 million. The average startup value when Azure Capital Partners invests is between $5 million and $10 million

Headquarters: USA

Investment Geography: USA, UK, Canada, Spain, Indonesia, Australia

Operating since: 2000

Stages: Post-Seed, Series A, Series B

Investment Focus: Enterprise Software, Enterprise Infrastructure, Hardware, AI, ML, Data Analytics, FinTech, Telcom, CyberSecurity, Digital Media, Gaming, E-commerce, Retail, EdTech, HealthTech, MarTech, Consumer Products, Personal Care, Beauty, Fashion, Dating, Social, Semiconductors, AgTech, BioTech, LegalTech, HRTech, TravelTech, AR, VR, Marketplaces 

Number of investments: 200

Number of exits: 78

Check size: $200k – $5m

Notable investments: Native, Clutch

Founders/Key People: Paul Ferris, Mike Kwatinetz 

Website: http://www.azurecap.com 

  1. Base10

Base10 Partners, founded by Adeyemi Ajao and TJ Nahigian, is a VC firm based in San Francisco. The firm focuses on investing in the automation of the real economy, targeting sectors like logistics, enterprise SaaS, healthcare, food, retail, operations, construction, and finance. Base10’s strategy is centered around investing in early-stage startups that use intelligent software and analytics technologies to disrupt these sectors.

Headquarters: USA

Investment Geography: USA, UK, Canada

Operating since: 2017

Stages: Seed, Series A

Investment Focus: Real Economy Automation, AI/ML, SaaS, Software, Enterprise (Finance, Food, Healthcare, Retail, Operations, Logistics, Construction)

Number of investments: 146

Number of exits: 21

Check size: $1m – $15m

Notable investments: Plaid, Figma

Founders/Key People: Adeyemi Ajao, TJ Nahigian

Website: https://base10.vc 

  1. Baseline Ventures

Baseline Ventures is a VC firm specializing in seed and growth-stage investments in tech. Founded in 2006 by Steve Anderson in San Francisco, California, the firm has been instrumental as the first seed investor in Instagram and an early investor in Twitter. Baseline Ventures is celebrated as one of Silicon Valley’s most successful and smallest investment firms. In terms of investment check size, Baseline Ventures offers checks based on the stage and needs of the startup. Their check sizes range from as low as $0 to $100K, going up to between $100K and $500K, and even as high as $500K to $1M. 

Headquarters: USA

Investment Geography: USA, Australia, Canada, Germany

Operating since: 2006

Stages: Seed, Series A

Investment Focus: FinTech, Enterprise/B2B Software, SaaS, CyberSecurity, Robotics, Mobile, Consumer Services, Digital Health, EdTech, Fashion, E-commerce, FoodTech, Gaming, Social, Marketplaces

Number of investments: 238

Number of exits: 102

Check size: $10k – $1m

Notable investments: SoFi, Instagram, Twitter

Founders/Key People: Steve Anderson

Website: https://www.baselinev.com 

  1. Benchmark

Benchmark has made a significant mark in the VC industry, with one of its most notable investments being a 1997 investment of $6.7 million in eBay for 22.1% of the company. The firm invests in various sectors, including mobile, marketplaces, social media, infrastructure, and enterprise software​. The firm has offices in San Francisco, California, and invests in seed-stage, early-stage, and later-stage companies. 

Headquarters: USA

Investment Geography: USA, UK, France, Israel, Germany, Sweden, Netherlands, Brazil, Ireland, Burma (Myanmar), Australia, Mexico, South Africa, Switzerland, Russia, China, Spain, Malaysia, Qatar, Canada, Belgium, Italy, Philippines, Singapore

Operating since: 1995 

Stages: Series A, Series B

Investment Focus: SaaS and Infrastructure, Social, Gaming, Mobile, Local 

Number of investments: 809

Number of exits: 325

Check size: $500k – $50m

Notable investments: Airtable, Contentful, Asana, eBay

Founders/Key People: Blake Robbins, Sarah Tavel

Website: https://www.benchmark.com 

  1. Liquid 2 Ventures

Liquid 2 Ventures, established in 2015 in San Francisco, California, is a venture capital firm co-founded by NFL legend Joe Montana alongside Michael Ma and Mike Miller. Specializing in seed-stage investments, the firm primarily targets early-stage technology startups. Liquid 2 Ventures has raised a total of $157.7 million across four funds, demonstrating a robust funding capacity. Liquid 2 Ventures stands out for its strategic approach to nurturing promising startups at their inception, guided by a team of experienced founders and investors.

Headquarters: USA

Investment Geography: United States, Canada, Mexico, United Kingdom, Israel, India, Chile, Nigeria, Colombia, Norway, Indonesia, France.

Operating since: 2015

Investment Focus: Enterprise Software,HealthTech,FinTech,Real Estate,EdTech,FoodTech,HRTech,Cyber Security,Transportation,Digital Media,LegalTech,MarTech,Fashion,Travel,Semiconductors,Robotics,Marketplaces.

Stages: Seed,Series A.

Number of investments: 381

Number of exits: 41

Check size: $100k – $1m

Notable investments: Ripplin, Whatnot.

Founders/Key People: Joe Montana, Mike Miller

Website: https://liquid2.vc

  1. M12 (CVC)

M12, formerly known as Microsoft Ventures, is a corporate venture capital subsidiary of Microsoft. Founded in March 2016 and based in San Francisco, California, M12’s primary mission is to be an active, strategic partner during a startup’s growth, typically investing between Series A and D rounds. M12 focuses on investing in companies operating in sectors like cloud infrastructure, and artificial intelligence, etc.

They have a specific interest in seed-stage technology companies disrupting the enterprise. M12 has made numerous diversity investments and notable exits, including companies like Bakkt, Markforged, and Vertical Aerospace​​​​​​​​​​.

Headquarters: USA

Investment Geography: United States, Israel, United Kingdom, Canada, Germany, France, China, Austria, Australia, Ireland, Norway, India.

Operating since: 2016

Investment Focus: Business Applications,Cloud Infrastructure,Cyber Security & Identity,Data & AI/ML,Developer Tools,Health Care/HealthTech & Life Sciences.

Stages: Pre-seed, Seed, Series A, Series B+.

Number of investments: 283

Number of exits: 30

Check size: $100K – $10M

Notable investments: CloudFlare, Outreach.

Founders/Key People: Peter Berg

Website: https://m12.vc

  1. Matrix Partners

Matrix Partners, established in 1977, is a U.S.-based private equity investment firm with a strong focus on venture capital investments. Headquartered in San Francisco, California, the firm primarily invests in seed and early-stage companies in the United States and India. The firm has made significant contributions to the venture capital landscape, supporting innovative startups and early-stage companies in various technology-driven fields​​​​​​​​.

Headquarters: USA

Investment Geography: United States, China, India, Singapore, Canada, United Kingdom, Hong Kong, Israel, Australia, France, Estonia, Denmark

Operating since: 1977.

Investment Focus: Consumer Tech,SaaS,Mobile,Hardware,E-commerce,Fashion,FoodTech,FinTech,Digital Media,PropTech,Mobility,Marketplaces,Enterprise Tech,Infrastructure,Enterprise Software,AI,Big Data,Data Analytics,Cyber Security,Telecom,Semiconductors,Wireless,HRTech.

Stage: Pre-Seed, Seed, Post-Seed, Series A, Series B+.

Number of investments: 896

Number of exits: 177

Check size: $100K – $50M

Notable investments: Apple, Canva

Founders/Key People: Mark McDonnell, Anthony Papalia

Website: https://www.matrix.vc

  1. Maverick Ventures

Maverick Ventures, founded in 2015, is a San Francisco-based venture capital firm. It operates as the venture arm of Maverick Capital, a hedge fund. Maverick Ventures specializes in investing in early-stage companies within the healthcare and technology sectors. By collaborating with Maverick Ventures, entrepreneurs gain access to the expertise of a dedicated team of venture partners, as well as the resources, reputation, and extensive network of a multi-billion dollar investment firm. Maverick Capital has been actively investing in early-stage companies for over two decades, emphasizing the depth of experience and market understanding that the venture arm brings to its investments.

Headquarters: USA

Investment Geography: United States, Israel, India, South Korea, China, Mexico, Ireland, Singapore, Switzerland, Denmark, United Kingdom, Canada.

Operating since: 1993.

Investment Focus: Digital Health & Wellness,Health Care/HealthTech/BioTech/MedTech ,Enterprise/B2B,AI/ML,SaaS/Software,Cyber Security, MarTech, HRTech, Consumer Tech/Consumer Internet,E-commerce,Marketplaces.

Stage: Pre-Seed, Seed, Post-Seed, Series A, Series B+.

Number of investments: 183

Number of exits: 35

Check size: $1M – $10M

Notable investments: Coupang, ConcertAI

Founders/Key People: Stephanie Mabunga, Richard Olson

Website: https://www.maverickventures.com/

  1. Mindset Ventures

Mindset Ventures is a venture capital firm with a primary investment focus in the United States and Israel. The firm specializes in backing B2B startups that demonstrate strong technological capabilities, particularly in sectors such as Agriculture, Financial Services, Healthcare, Cybersecurity, and Enterprise Software. Established as an early-stage venture capital firm, Mindset Ventures operates from offices located in São Paulo, San Francisco, and Tel-Aviv, reflecting its international presence and commitment. 

Headquarters: USA

Investment Geography: United States, Israel, Brazil, Canada.

Operating since: 2016.

Investment Focus: Enterprise SaaS Strong Tech (Agriculture,Financial Services, HealthCare, Cybersecurity,Education).

Stage: Pre-Seed, Seed, Post-Seed, Series A, Series B.

Number of investments: 74

Number of exits: 9

Check size: $200K – $2M

Notable investments: Turing, Brex.

Founders/Key People: Camila Potenza, Daniel Ibri

Website: https://mindset.ventures

  1. Moxxie Ventures

Moxxie Ventures, founded in 2019, is a seed-stage venture capital firm based in Mountain View, California. Moxxie Ventures is known for its proactive approach to influencing the future positively by investing in founders who improve life and work. Their philosophy emphasizes backing exceptional founders in early-stage technology companies. 

Headquarters: USA

Investment Geography: United States, Canada, Netherlands, United Kingdom, Kenya.

Operating since: 2019.

Investment Focus: Consumer Internet,Enterprise/B2B, SaaS/Software, FinTech, HealthTech/Digital Health,Climate.

Stage: Seed, Post-Seed, Series A, Series B.

Number of investments: 35

Number of exits: 0

Check size: $200K – $2M

Notable investments: Daily, Certn

Founders/Key People: Alex Roetter

Website: https://www.moxxie.vc

  1. NextWorld Capital

NextWorld Capital, founded in 2008 and based in San Francisco, California, is a venture capital firm that specializes in investing in enterprise technology startups. The firm focuses on helping these startups grow into global leaders, playing a pivotal role in their development. The firm’s primary investment sectors include software services and telecom, focusing on business models like B2B and SAAS​​​​​​​​.

Headquarters: USA

Investment Geography: USA.

Operating since: 2009.

Investment Focus: Enterprise Tech,Enterprise Platform,Enterprise Software,B2B SaaS,B2B Marketplace.

Stage: Seed, Post-Seed, Series A, Series B+.

Number of investments: 51

Number of exits: 10

Check size: $5M – $50M

Notable investments: Gong.io, DataStax

Founders/Key People: Jean-Christoph Gaillard

Website: https://www.nextworldcap.com

  1. NFX

NFX Capital, founded in 2015, is a venture capital firm based in San Francisco, California, with additional offices in Herzlia, Israel, and Palo Alto, California. The firm invests across a diverse range of sectors, with a focus on Latin America and Israel. NFX Capital particularly emphasizes early-stage venture investments, with Fund II established in 2019 having a size of $338M. This fund reflects their commitment to early-stage venture capital, supporting startups in critical growth phases. Additionally, NFX Capital is known for its expertise in the edtech sector, reflecting a broad interest in transformative technology sectors​​​​​​​​.

Headquarters: USA

Investment Geography: United States, Israel, United Kingdom, Canada, Brazil, Sweden, France, India, Türkiye, Belgium, Netherlands, Spain.

Operating since: 2015.

Investment Focus: Network Effects,B2B Marketplace/B2B Services,Consumer Marketplace/Consumer Internet,Communities,Digital Media/Social Media, BioTech/Tech-Bio,SaaS/Software.

Stage: Seed, Post-Seed, Series A, Series B.

Number of investments: 470

Number of exits: 30

Check size: $500K – $5M

Notable investments: DoorDash, Patreon

Founders/Key People: Pete Flint, Stan Chudnovsky

Website: https://www.nfx.com

Conclusion

That’s a wrap on our tour of the 19 top venture capital firms in San Francisco. Whether you’re at the idea stage or ready to scale, one of these firms could be the key to unlocking your startup’s potential. Remember, it’s all about finding that perfect fit – a VC that not just funds, but fuels your vision with the right resources and industry insights.

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